Issue 15, 2010
From the journal:

Chemical Communications

Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAMdendrimer nanoconjugate†

Seok Ki Choi,*a   Thommey Thomas,a   Ming-Hsin Li,a   Alina Kotlyar,a   Ankur Desaia  and  James R. Baker, Jr.*a  

* Corresponding authors

a Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Medical School, Ann Arbor, USA
E-mail: skchoi@umich.edu, jbakerjr@med.umich.edu
Fax: (734) 615-0621
Tel: (734) 615-0618

Abstract

We report the synthesis and in vitro evaluation of folate receptor-targeted nanoconjugate that releases its therapeutic payload via a photochemical mechanism.

Graphical abstract: Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAMdendrimer nanoconjugate

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Article information

DOI
https://doi.org/10.1039/B927215C
Article type
Communication
Submitted
23 Dec 2009
Accepted
22 Jan 2010
First published
06 Feb 2010

Chem. Commun., 2010,46, 2632-2634

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Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAMdendrimer nanoconjugate

S. Ki Choi, T. Thomas, M. Li, A. Kotlyar, A. Desai and J. R. Baker, Jr., Chem. Commun., 2010, 46, 2632 DOI: 10.1039/B927215C

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