Issue 14, 2010
From the journal:

Chemical Communications

Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(iii) complex†

Ga-Lai Law,a   Cornelia Man,b   David Parker*a  and  James W. Waltona  

* Corresponding authors

a Department of Chemistry, Durham University, South Road, Durham, UK
E-mail: david.parker@dur.ac.uk

b Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hunghom, Hong Kong, China

Abstract

The emission intensity of a monocationic Tb or Eu(III) complex of a bis(1-azaxanthone) ligand is enhanced in the presence of serum albumin; the lanthanide complex stains dividing cells, allowing visualisation of mitotic chromosomes.

Graphical abstract: Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(iii) complex

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Article information

DOI
https://doi.org/10.1039/B924679G
Article type
Communication
Submitted
24 Nov 2009
Accepted
16 Jan 2010
First published
02 Feb 2010

Chem. Commun., 2010,46, 2391-2393

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Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(III) complex

G. Law, C. Man, D. Parker and J. W. Walton, Chem. Commun., 2010, 46, 2391 DOI: 10.1039/B924679G

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