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Issue 5, 2010
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Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation

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Abstract

Direct selective palladium catalyzed C–H functionalization has become a highly attractive strategy in organic synthesis and represents a highly desirable goal. Compared with cross-coupling reactions of C–H bonds with aryl or alkyl halides/pseudohalides, the strategy of cross-coupling reactions of C–H bonds with organometallic reagents is of great significance and obvious advantages. This feature article provides a comprehensive summary of recent advances and an intensive analysis on Pd-catalyzed C–H activation and oxidative coupling with various organometallic reagents.

Graphical abstract: Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation

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Article information


Submitted
29 Apr 2009
Accepted
25 Nov 2009
First published
05 Jan 2010

Chem. Commun., 2010,46, 677-685
Article type
Feature Article

Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation

C. Sun, B. Li and Z. Shi, Chem. Commun., 2010, 46, 677
DOI: 10.1039/B908581E

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