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Issue 9, 2010

Ionic liquid-assisted transdermal delivery of sparingly soluble drugs

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Abstract

We report the first successful application of a novel IL-assisted non-aqueous microemulsion stabilized by a blend of two nontoxic surfactants, polyoxyethylene sorbitan monooleate (Tween-80), and sorbitan laurate (Span-20) for transdermal delivery of acyclovir, which is insoluble or sparingly soluble in water and most common organic liquids.

Graphical abstract: Ionic liquid-assisted transdermal delivery of sparingly soluble drugs

Supplementary files

Article information


Submitted
15 Apr 2009
Accepted
25 Nov 2009
First published
14 Jan 2010

Chem. Commun., 2010,46, 1452-1454
Article type
Communication

Ionic liquid-assisted transdermal delivery of sparingly soluble drugs

M. Moniruzzaman, Y. Tahara, M. Tamura, N. Kamiya and M. Goto, Chem. Commun., 2010, 46, 1452 DOI: 10.1039/B907462G

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