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Issue 19, 2010
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A nano-fibrous assembly of collagen–hyaluronic acid for controlling cell-adhesive properties

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Abstract

We report an artificially fabricated extracellular matrix (ECM)-like nanostructure, which utilizes self-assembly of collagen and hyaluronic acid in a quasi two-dimensional space of tens-of-nm thickness, displaying different cellular adhesive characteristics depending on the structural properties between the fibril and non-fibril elements. This nano-fibrous assembly will facilitate a mechano-biological approach for the development of tissue-engineering scaffolds.

Graphical abstract: A nano-fibrous assembly of collagen–hyaluronic acid for controlling cell-adhesive properties

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Supplementary files

Article information


Submitted
14 Jun 2010
Accepted
15 Jul 2010
First published
20 Aug 2010

Soft Matter, 2010,6, 4672-4676
Article type
Communication

A nano-fibrous assembly of collagenhyaluronic acid for controlling cell-adhesive properties

T. Fujie, S. Furutate, D. Niwa and S. Takeoka, Soft Matter, 2010, 6, 4672
DOI: 10.1039/C0SM00527D

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