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Issue 5, 2010
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Recent advances in the design of bioconjugates from controlled/living radical polymerization

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Abstract

Since its discovery, controlled/living radical polymerization (CLRP) has proven to be a mature technology for building tailor-made (block) copolymers, functional polymers and polymers with a wide range of biological recognition. Due to these considerable advantages over other synthetic approaches, CLRP techniques have been successfully exploited to construct novel polymer-protein/peptide bioconjugates with a high level of structural control and varied interesting, somehow unexpected, features. A comprehensive review of the recent advances in the rapidly expanding field of bioconjugation is presented and outlines work up to early 2010.

Graphical abstract: Recent advances in the design of bioconjugates from controlled/living radical polymerization

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Article information


Submitted
29 Nov 2009
Accepted
05 Jan 2010
First published
29 Jan 2010

Polym. Chem., 2010,1, 563-598
Article type
Review Article

Recent advances in the design of bioconjugates from controlled/living radical polymerization

B. Le Droumaguet and J. Nicolas, Polym. Chem., 2010, 1, 563
DOI: 10.1039/B9PY00363K

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