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Issue 14, 2010
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Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones

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Abstract

A convenient synthesis of benzyl-γ-butyrolactone derivatives via intramolecular Michael addition reaction of nitro-substituted aryl allyl β-ketocarboxylates is reported. The method features simple operation, mild reaction conditions and high efficiency.

Graphical abstract: Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones

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Publication details

The article was received on 25 Nov 2009, accepted on 28 Apr 2010 and first published on 20 May 2010


Article type: Paper
DOI: 10.1039/B924770J
Org. Biomol. Chem., 2010,8, 3207-3210

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    Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones

    H. He, L. Dai and S. You, Org. Biomol. Chem., 2010, 8, 3207
    DOI: 10.1039/B924770J

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