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Issue 3, 2010
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(−)-Bacillamide C: the convergent approach

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Abstract

The newly discovered natural product bacillamide C and several derivatives were convergently synthesized for the first time and in only three steps. The key transformation constitutes a thiazole Ugi multicomponent reaction. These compounds will serve to elucidate chemical biology and SAR of this potent anti-algae natural product and shows the synthetic pathway to related natural products.

Graphical abstract: (−)-Bacillamide C: the convergent approach

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Article information


Submitted
04 Sep 2009
Accepted
11 Nov 2009
First published
26 Nov 2009

Org. Biomol. Chem., 2010,8, 529-532
Article type
Communication

(−)-Bacillamide C: the convergent approach

W. Wang, S. Joyner, K. A. S. Khoury and A. Dömling, Org. Biomol. Chem., 2010, 8, 529
DOI: 10.1039/B918214D

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