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Issue 1, 2010
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Catalytic asymmetric conjugate addition of dialkylzinc reagents to α,β-unsaturated sulfones

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Abstract

An efficient method is reported for the highly enantioselective copper-catalyzed conjugate addition of dialkylzinc reagents to α,β-unsaturated sulfones using a monodentate phosphoramidite ligand.

Graphical abstract: Catalytic asymmetric conjugate addition of dialkylzinc reagents to α,β-unsaturated sulfones

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Article information


Submitted
21 Aug 2009
Accepted
21 Sep 2009
First published
01 Oct 2009

Org. Biomol. Chem., 2010,8, 47-49
Article type
Communication

Catalytic asymmetric conjugate addition of dialkylzinc reagents to α,β-unsaturated sulfones

P. H. Bos, B. Maciá, M. Á. Fernández-Ibáñez, A. J. Minnaard and B. L. Feringa, Org. Biomol. Chem., 2010, 8, 47
DOI: 10.1039/B917269F

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