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Issue 4, 2010
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Complexity and simplicity in the biosynthesis of enediynenatural products

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Abstract

Covering: up to the end of 2009

The review highlights the recent progress on the elucidation of the biosynthetic mechanism of enediyne natural products. A large body of knowledge has been gathered from the genetic, biochemical and structural studies since the sequencing of the first two enediyne gene clusters in 2002. Primary attention is devoted to the novel pathways and enzymes in the biosynthesis of the enediyne warhead as well as the peripheral moieties.

Graphical abstract: Complexity and simplicity in the biosynthesis of enediyne natural products

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Article information


Submitted
15 Dec 2009
First published
18 Feb 2010

Nat. Prod. Rep., 2010,27, 499-528
Article type
Review Article

Complexity and simplicity in the biosynthesis of enediyne natural products

Z. Liang, Nat. Prod. Rep., 2010, 27, 499 DOI: 10.1039/B908165H

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