- Bacterial strains and plasmids used in this study (Table S1), characterization of AziB1 as a P450 enzyme (Fig. S1), effect of pH on the relative activity of AziB1 (Fig. S2), time course of AziB1-catalyzed hydroxylation (Fig. S3), characterization of AziB2 as a SAM-dependent enzyme (Fig. S4), effect of pH on the relative activity of AziB2 (Fig. S5), time course of AziB1-catalyzed O-methylation (Fig. S6), effect of divalent metal ions on the relative activity of AziB2 (Fig. S7), and selected modes of bacterial iterative type I PKSs-post modifications and incorporation for aromatic compounds (Fig. S8) PDF (554K)
Biosynthesis of 3-methoxy-5-methyl naphthoic acid and its incorporation into the antitumor antibiotic azinomycin B
W. Ding, W. Deng, M. Tang, Q. Zhang, G. Tang, Y. Bi and W. Liu, Mol. BioSyst., 2010, 6, 1071 DOI: 10.1039/B926358F
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