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Issue 19, 2010
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Programmable diagnostic devices made from paper and tape

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This paper describes three-dimensional microfluidic paper-based analytical devices (3-D µPADs) that can be programmed (postfabrication) by the user to generate multiple patterns of flow through them. These devices are programmed by pressing single-use ‘on’ buttons, using a stylus or a ballpoint pen. Pressing a button closes a small space (gap) between two vertically aligned microfluidic channels, and allows fluids to wick from one channel to the other. These devices are simple to fabricate, and are made entirely out of paper and double-sided adhesive tape. Programmable devices expand the capabilities of µPADs and provide a simple method for controlling the movement of fluids in paper-based channels. They are the conceptual equivalent of field-programmable gate arrays (FPGAs) widely used in electronics.

Graphical abstract: Programmable diagnostic devices made from paper and tape

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Article information

12 May 2010
24 Jun 2010
First published
30 Jul 2010

Lab Chip, 2010,10, 2499-2504
Article type

Programmable diagnostic devices made from paper and tape

A. W. Martinez, S. T. Phillips, Z. Nie, C. Cheng, E. Carrilho, B. J. Wiley and G. M. Whitesides, Lab Chip, 2010, 10, 2499
DOI: 10.1039/C0LC00021C

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