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Issue 16, 2010
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Real-time, step-wise, electrical detection ofprotein molecules using dielectrophoretically aligned SWNT-film FET aptasensors

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Abstract

Aptamer functionalized addressable SWNT-film arrays between cantilever electrodes were successfully developed for biosensor applications. Dielectrophoretically aligned SWNT suspended films made possible highly specific and rapid detection of target proteins with a large binding surface area. Thrombin aptamer immobilized SWNT-film FET biosensor resulted in a real-time, label-free, and electrical detection of thrombin molecules down to a concentration of ca. 7 pM with a step-wise rapid response time of several seconds.

Graphical abstract: Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors

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Article information


Submitted
30 Apr 2010
Accepted
18 Jun 2010
First published
09 Jul 2010

Lab Chip, 2010,10, 2052-2056
Article type
Communication

Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors

T. An, K. S. Kim, S. K. Hahn and G. Lim, Lab Chip, 2010, 10, 2052 DOI: 10.1039/C005276K

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