Jump to main content
Jump to site search

Issue 10, 2010
Previous Article Next Article

Nanopatterning molecularly imprinted polymers by soft lithography: a hierarchical approach

Author affiliations

Abstract

We use soft lithography to pattern molecularly imprinted polymers (MIPs) at the nanoscale. Patterning occurs via a micro transfer molding process associated with an edge effect. We show using fluorescence microscopy that the nanopatterned synthetic receptors specifically recognize and bind a model target, dansyl-L-phenylalanine. We also demonstrate using AFM a specific swelling of the MIP pattern in the presence of the analyte. We believe that this opens new opportunities for the application of MIPs in microsensors and microbiochips, for example in environmental analysis and biomedical diagnostics.

Graphical abstract: Nanopatterning molecularly imprinted polymers by soft lithography: a hierarchical approach

Back to tab navigation

Supplementary files

Article information


Submitted
19 Nov 2009
Accepted
25 Jan 2010
First published
11 Feb 2010

Lab Chip, 2010,10, 1316-1318
Article type
Technical Note

Nanopatterning molecularly imprinted polymers by soft lithography: a hierarchical approach

H. Lalo, C. Ayela, E. Dague, C. Vieu and K. Haupt, Lab Chip, 2010, 10, 1316
DOI: 10.1039/B924315A

Social activity

Search articles by author

Spotlight

Advertisements