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Issue 9, 2010
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Elastin-based materials

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Elastin is a versatile elastic protein that dominates flexible tissues capable of recoil, and facilitates commensurate cell interactions in these tissues in all higher vertebrates. Elastin's persistence and insolubility hampered early efforts to construct versatile biomaterials. Subsequently the field has progressed substantially through the adapted use of solubilized elastin, elastin-based peptides and the increasing availability of recombinant forms of the natural soluble elastin precursor, tropoelastin. These interactions allow for the formation of a sophisticated range of biomaterial constructs and composites that benefit from elastin's physical properties of innate assembly and elasticity, and cell interactive properties as discussed in this tutorial review.

Graphical abstract: Elastin-based materials

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Publication details

The article was received on 03 Feb 2010 and first published on 07 May 2010

Article type: Tutorial Review
DOI: 10.1039/B919452P
Chem. Soc. Rev., 2010,39, 3371-3379

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    Elastin-based materials

    J. F. Almine, D. V. Bax, S. M. Mithieux, L. Nivison-Smith, J. Rnjak, A. Waterhouse, S. G. Wise and A. S. Weiss, Chem. Soc. Rev., 2010, 39, 3371
    DOI: 10.1039/B919452P

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