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Issue 3, 2010
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Tether forces in DNAelectrophoresis

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This tutorial review introduces the concepts necessary for understanding the generation of forces on charged objects in solution by externally applied electric fields. We focus on simple, idealized cases and conceptual understanding rather than quantitative modeling. We also discuss experiments in which electrophoretic forces on DNA were directly measured. This review is aimed at readers interested in the fundamentals of electrophoresis in general, as well as those with more specific interests in DNA electrophoresis, nanopores and optical tweezers.

Graphical abstract: Tether forces in DNA electrophoresis

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Article information

01 Jul 2009
First published
03 Nov 2009

Chem. Soc. Rev., 2010,39, 939-947
Article type
Tutorial Review

Tether forces in DNA electrophoresis

U. F. Keyser, S. van Dorp and S. G. Lemay, Chem. Soc. Rev., 2010, 39, 939
DOI: 10.1039/B902072C

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