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Issue 2, 2010
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Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

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Abstract

In this tutorial review, an effort towards presentation of a comprehensive account of the recent developments on various kinds of artemisinin derivatives including artemisinin dimers, trimers and tetramers has been made and their efficacy towards malaria parasites and different cancer cells lines was compared with that of artemisinins, and various other anti-malarial and anti-cancer drugs. It is expected that this review will provide first-hand information on artemisinin chemistry to organic/medicinal chemists, and pharmacologists working on anticancer and anti-malarial drug development.

Graphical abstract: Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

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Article information


Submitted
03 Feb 2009
First published
24 Aug 2009

Chem. Soc. Rev., 2010,39, 435-454
Article type
Tutorial Review

Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

D. Chaturvedi, A. Goswami, P. Pratim Saikia, N. C. Barua and P. G. Rao, Chem. Soc. Rev., 2010, 39, 435
DOI: 10.1039/B816679J

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