Issue 18, 2010
From the journal:

Chemical Communications

Solvent free catalytic C–H functionalisation†‡

Robin B. Bedford,*a   Charlotte J. Mitchellb  and  Ruth L. Webstera  

* Corresponding authors

a School of Chemistry, University of Bristol, Cantock's Close, Bristol, UK
E-mail: r.bedford@bristol.ac.uk

b GlaxoSmithKline, Stevenage, UK

Abstract

Solvent-free reaction conditions facilitate a range of aromatic C–H functionalisations that traditionally require acidic or disfavoured solvents. These reactions include selective ortho- and meta-arylation of aryl carbamates and anilides and selective halogenation reactions.

Graphical abstract: Solvent free catalytic C–H functionalisation

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Article information

DOI
https://doi.org/10.1039/C003074K
Article type
Communication
Submitted
12 Feb 2010
Accepted
12 Mar 2010
First published
30 Mar 2010

Chem. Commun., 2010,46, 3095-3097

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Solvent free catalytic C–H functionalisation

R. B. Bedford, C. J. Mitchell and R. L. Webster, Chem. Commun., 2010, 46, 3095 DOI: 10.1039/C003074K

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