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Issue 18, 2010
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Developing an anion host for lipid A binding and antibacterial activity

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Abstract

New structural amphiphiles 2a and 2b bind the diphosphate lipid A anion and show potential as lead compounds for the development of novel antibacterial agents.

Graphical abstract: Developing an anion host for lipid A binding and antibacterial activity

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Supplementary files

Article information


Submitted
30 Nov 2009
Accepted
01 Mar 2010
First published
18 Mar 2010

Chem. Commun., 2010,46, 3197-3199
Article type
Communication

Developing an anion host for lipid A binding and antibacterial activity

L. C. Henderson, J. Li, R. L. Nation, T. Velkov and F. M. Pfeffer, Chem. Commun., 2010, 46, 3197
DOI: 10.1039/B925135A

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