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Issue 43, 2010
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Enhancement of antimicrobial activity by synthetic ion channel synergy

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Abstract

Hydraphile synthetic ion channels were found to enhance the cytotoxicity to E. coli and B. subtilis of erythromycin, kanamycin, rifampicin, and tetracycline when co-administered with the antibiotic at sublethal concentrations of channel.

Graphical abstract: Enhancement of antimicrobial activity by synthetic ion channel synergy

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Article information


Submitted
09 Aug 2010
Accepted
24 Sep 2010
First published
08 Oct 2010

Chem. Commun., 2010,46, 8166-8167
Article type
Communication

Enhancement of antimicrobial activity by synthetic ion channel synergy

J. L. Atkins, M. B. Patel, Z. Cusumano and G. W. Gokel, Chem. Commun., 2010, 46, 8166
DOI: 10.1039/C0CC03138K

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