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Issue 6, 2010
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Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes

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Abstract

FRET analysis has been used to examine the folded conformations and differing kinetic stabilities of two DNA G-quadruplexes (c-kit 1 and c-kit 2) derived from sequences found in the promoter of the c-kit proto-oncogene.

Graphical abstract: Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes

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Article information


Submitted
06 Oct 2009
Accepted
19 Nov 2009
First published
10 Dec 2009

Chem. Commun., 2010,46, 946-948
Article type
Communication

Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes

A. Fegan, P. S. Shirude, L. Ying and S. Balasubramanian, Chem. Commun., 2010, 46, 946
DOI: 10.1039/B920680A

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