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Issue 9, 2010
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Ionic liquid-assisted transdermal delivery of sparingly soluble drugs

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Abstract

We report the first successful application of a novel IL-assisted non-aqueous microemulsion stabilized by a blend of two nontoxic surfactants, polyoxyethylene sorbitan monooleate (Tween-80), and sorbitan laurate (Span-20) for transdermal delivery of acyclovir, which is insoluble or sparingly soluble in water and most common organic liquids.

Graphical abstract: Ionic liquid-assisted transdermal delivery of sparingly soluble drugs

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Publication details

The article was received on 15 Apr 2009, accepted on 25 Nov 2009 and first published on 14 Jan 2010


Article type: Communication
DOI: 10.1039/B907462G
Chem. Commun., 2010,46, 1452-1454

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    Ionic liquid-assisted transdermal delivery of sparingly soluble drugs

    M. Moniruzzaman, Y. Tahara, M. Tamura, N. Kamiya and M. Goto, Chem. Commun., 2010, 46, 1452
    DOI: 10.1039/B907462G

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