Jump to main content
Jump to site search

Issue 21, 2009
Previous Article Next Article

Small monodisperse unilamellar vesicles from binary copolymer mixtures

Author affiliations

Abstract

Small unilamellar vesicles are formed spontaneously by simple mixing of lamellae-forming diblock copolymer PB10PE10 (PB is a butylene oxide block, and PE an ethylene oxide block) with micelle-forming diblock copolymer PB10PE18. Small angle neutron scattering (SANS) measurements show that the average vesicle radius may be as small as 30 nm with a polydispersity index of 0.15. From the SANS measurements it can also be deduced that the vesicles have a 3.4 nm thick hydrophobic membrane core and a 1.2 nm hydrophilic corona. Furthermore, it is seen that the vesicles coexist with spherical micelles. The influence of the mixing ratio as well as the concentration of the polymeric components is studied. Results of the micelle size, the vesicle size and the shell structure are confirmed by cryo-TEM measurements.

Graphical abstract: Small monodisperse unilamellar vesicles from binary copolymer mixtures

Back to tab navigation

Publication details

The article was received on 05 Mar 2009, accepted on 16 Jul 2009 and first published on 12 Aug 2009


Article type: Paper
DOI: 10.1039/B904522H
Citation: Soft Matter, 2009,5, 4169-4172
  •   Request permissions

    Small monodisperse unilamellar vesicles from binary copolymer mixtures

    F. Li, S. Prévost, R. Schweins, A. T. M. Marcelis, F. A. M. Leermakers, M. A. Cohen Stuart and E. J. R. Sudhölter, Soft Matter, 2009, 5, 4169
    DOI: 10.1039/B904522H

Search articles by author

Spotlight

Advertisements