4-Aminoproline-based arginine-glycine-aspartate integrin binders with exposed ligation points: practical in-solution synthesis, conjugation and binding affinity evaluation†
Abstract
An expedient and practical in-solution synthesis of three new
* Corresponding authors
a
Dipartimento Farmaceutico, Università degli Studi di Parma, Viale G. P. Usberti 27A, I-43100 Parma, Italy
E-mail:
lucia.battistini@unipr.it, giovanni.casiraghi@unipr.it
Fax: +39-0521-905006
Tel: +39-0521-906040
b Istituto di Chimica Biomolecolare del CNR, Traversa La Crucca 3, I-07040 Li Punti, Sassari, Italy
c Centro Interdipartimentale Studi Biomolecolari e Applicazioni Industriali, Università degli Studi di Milano, Via Fantoli 16/15, I-20138 Milano, Italy
d Istituto di Scienze e Tecnologie Molecolari del CNR, Via Fantoli 16/15, I-20138 Milano, Italy
An expedient and practical in-solution synthesis of three new
L. Battistini, P. Burreddu, P. Carta, G. Rassu, L. Auzzas, C. Curti, F. Zanardi, L. Manzoni, E. M. V. Araldi, C. Scolastico and G. Casiraghi, Org. Biomol. Chem., 2009, 7, 4924 DOI: 10.1039/B914836A
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