Issue 19, 2009

Lewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates

Abstract

The addition of a Lewis acidic metal triflate salt Mg(OTf)2 as co-catalyst in the CpRu-catalyzed decarboxylative allylation of in situ-generated ketone enolates allows the reaction to proceed at lower temperature with higher regio- and enantioselectivity. Even so-far-unreactive substrates react.

Graphical abstract: Lewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates

Supplementary files

Article information

Article type
Paper
Submitted
28 May 2009
Accepted
18 Jun 2009
First published
28 Jul 2009

Org. Biomol. Chem., 2009,7, 4057-4061

Lewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates

D. Linder, M. Austeri and J. Lacour, Org. Biomol. Chem., 2009, 7, 4057 DOI: 10.1039/B910475E

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