Issue 15, 2009

“Isocyanide-free” Ugi reactions

Abstract

High-yielding Ugi reactions have been carried out with in situ-prepared isocyanides, derived from the reaction of bromide derivatives with silver and potassium cyanide, thus alleviating the burden of the preparation, purification and subsequent use of isocyanides in multicomponent reactions.

Graphical abstract: “Isocyanide-free” Ugi reactions

Supplementary files

Article information

Article type
Communication
Submitted
30 Apr 2009
Accepted
05 Jun 2009
First published
17 Jun 2009

Org. Biomol. Chem., 2009,7, 3024-3026

Isocyanide-free” Ugi reactions

L. El Kaïm, L. Grimaud and A. Schiltz, Org. Biomol. Chem., 2009, 7, 3024 DOI: 10.1039/B908541F

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