Issue 1, 2009

Thermal epimerization of diastereomeric Grignard reagents

Abstract

Thermal epimerization is the key to changing the endo-to-exo ratio of the diastereomeric bornyl and fenchyl Grignard reagents from 67 : 33 to 96 : 4 and from 20 : 80 to 80 : 20, respectively.

Graphical abstract: Thermal epimerization of diastereomeric Grignard reagents

Supplementary files

Article information

Article type
Communication
Submitted
28 Oct 2008
Accepted
30 Oct 2008
First published
13 Nov 2008

Org. Biomol. Chem., 2009,7, 41-42

Thermal epimerization of diastereomeric Grignard reagents

J. Beckmann and A. Schütrumpf, Org. Biomol. Chem., 2009, 7, 41 DOI: 10.1039/B819178F

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