Issue 21, 2009
From the journal:

Lab on a Chip

Rapid switching of chemical signals in microfluidic devices†

Albert J. Bae,ab   Carsten Beta*ac  and  Eberhard Bodenschatzab  

* Corresponding authors

a Max Planck Institute for Dynamics and Self-Organization, Am Fassberg 11, Göttingen, Germany

b Laboratory of Atomic and Solid State Physics, Department of Physics, Cornell University, Ithaca, NY, USA

c Institute of Physics und Astronomy, University of Potsdam, Karl-Liebknecht-Str. 24/25, Potsdam-Golm, Germany

Abstract

We present an analysis of concentration switching times in microfluidic devices. The limits of rapid switching are analyzed based on the theory of dispersion by Taylor and Aris and compared to both experiments and numerical simulations. We focus on switching times obtained by photo-activation of caged compounds in a micro-flow (flow photolysis). The performance of flow photolysis is compared to other switching techniques. A flow chart is provided to facilitate the application of our theoretical analysis to microfluidic switching devices.

Graphical abstract: Rapid switching of chemical signals in microfluidic devices

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Article information

DOI
https://doi.org/10.1039/B905521E
Article type
Paper
Submitted
18 Mar 2009
Accepted
15 Jun 2009
First published
03 Jul 2009

Lab Chip, 2009,9, 3059-3065

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Rapid switching of chemical signals in microfluidic devices

A. J. Bae, C. Beta and E. Bodenschatz, Lab Chip, 2009, 9, 3059 DOI: 10.1039/B905521E

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