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Issue 5, 2009
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Postsynthetic modification of metal–organic frameworks

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The modification of metal–organic frameworks (MOFs) in a postsynthetic scheme is discussed in this critical review. In this approach, the MOF is assembled and then modified with chemical reagents with preservation of the lattice structure. Recent findings show amide couplings, isocyanate condensations, ‘click’ chemistry, and other reactions are suitable for postsynthetic modification (PSM). In addition, a number of MOFs, from IRMOF-3 to ZIF-90, are amenable to PSM. The generality of PSM, in both scope of chemical reactions and range of suitable MOFs, clearly indicates that the approach is broadly applicable. Indeed, the rapid increase in reports on PSM demonstrates this methodology will play an increasingly important role in the development of MOFs for the foreseeable future (117 references).

Graphical abstract: Postsynthetic modification of metal–organic frameworks

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The article was received on 16 Sep 2008 and first published on 20 Jan 2009

Article type: Critical Review
DOI: 10.1039/B802258P
Chem. Soc. Rev., 2009,38, 1315-1329

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    Postsynthetic modification of metal–organic frameworks

    Z. Wang and S. M. Cohen, Chem. Soc. Rev., 2009, 38, 1315
    DOI: 10.1039/B802258P

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