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Issue 38, 2009
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β-Amidoaldehydes viaoxazolinehydroformylation

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Abstract

4-Substituted oxazolines, which are readily synthesized from naturally occurring α-amino acids, are converted efficiently and stereospecifically to β-amidoaldehydes in the presence of synthesis gas and catalytic dicobalt octacarbonyl.

Graphical abstract: β-Amidoaldehydes viaoxazolinehydroformylation

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Publication details

The article was received on 09 Jul 2009, accepted on 10 Aug 2009 and first published on 01 Sep 2009


Article type: Communication
DOI: 10.1039/B913698C
Citation: Chem. Commun., 2009,0, 5704-5706

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    β-Amidoaldehydes viaoxazolinehydroformylation

    D. S. Laitar, J. W. Kramer, B. T. Whiting, E. B. Lobkovsky and G. W. Coates, Chem. Commun., 2009, 0, 5704
    DOI: 10.1039/B913698C

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