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Issue 45, 2009
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Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides and carbon monoxide

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Abstract

Regioselective synthesis of halohydrin esters was achieved by (1) the reaction of acyl halides with epoxides and (2) the rhodium-catalyzed three-component coupling reaction of alkyl halides, carbon monoxide, and epoxides.

Graphical abstract: Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides and carbon monoxide

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Publication details

The article was received on 01 Jul 2009, accepted on 06 Oct 2009 and first published on 16 Oct 2009


Article type: Communication
DOI: 10.1039/B912907C
Citation: Chem. Commun., 2009,0, 6970-6972
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    Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides and carbon monoxide

    K. Nakano, S. Kodama, Y. Permana and K. Nozaki, Chem. Commun., 2009, 0, 6970
    DOI: 10.1039/B912907C

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