Computational design, synthesis, and evaluation of miniproteins as androgen receptor coactivator mimics†
Abstract
Insertion of 3 to 4 mutations, based on in silico modelling, in a diverse set of
* Corresponding authors
a Chemical Genomics Centre of the Max Planck Society, Otto-Hahn Straße 15, 44227 Dortmund, Germany
b Computational Drug Discovery, Centre for Molecular and Biomolecular Informatics, Radboud University, Nijmegen, The Netherlands
c Molecular Design & Informatics, Schering-Plough, Oss, The Netherlands
d
Laboratory of Chemical Biology, Department of Biomedical Engineering, Technische Universiteit Eindhoven, Den Dolech 2, Eindhoven, The Netherlands
E-mail:
l.brunsveld@tue.nl
Fax: +31 402478367
Insertion of 3 to 4 mutations, based on in silico modelling, in a diverse set of
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