Issue 33, 2009
From the journal:

Chemical Communications

Small molecule microarray-facilitated screening of affinity-based probes (AfBPs) for γ-secretase†

Haibin Shi,ac   Kai Liu,b   Ashley Xua  and  Shao Q. Yao*abc  

* Corresponding authors

a Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore

b Department of Biological Sciences, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore

c NUS MedChem Program of the Life Sciences Institute, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
E-mail: chmyaosq@nus.edu.sg
Fax: +1 (65) 6779169
Tel: +1 (65) 65162925

Abstract

A small molecule microarray (SMM) platform is developed herein, which enables high-throughput discovery of affinity-based probes (AfBPs) against γ-secretase.

Graphical abstract: Small molecule microarray-facilitated screening of affinity-based probes (AfBPs) for γ-secretase

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Article information

DOI
https://doi.org/10.1039/B910611A
Article type
Communication
Submitted
01 Jun 2009
Accepted
25 Jun 2009
First published
14 Jul 2009

Chem. Commun., 2009, 5030-5032

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Small molecule microarray-facilitated screening of affinity-based probes (AfBPs) for γ-secretase

H. Shi, K. Liu, A. Xu and S. Q. Yao, Chem. Commun., 2009, 5030 DOI: 10.1039/B910611A

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