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Issue 32, 2009
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A catalytic synthesis of selectively substituted biaryls through sequential intermolecular coupling involving arene and ketone C–H bond functionalization

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Abstract

Selectively substituted biaryls containing a ketone unit are obtained under mild conditions in satisfactory yields by a simple reaction of ortho-substituted aryl iodides and ketones in the presence of palladium and norbornene as catalysts.

Graphical abstract: A catalytic synthesis of selectively substituted biaryls through sequential intermolecular coupling involving arene and ketone C–H bond functionalization

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Publication details

The article was received on 08 May 2009, accepted on 12 Jun 2009 and first published on 01 Jul 2009


Article type: Communication
DOI: 10.1039/B909207B
Citation: Chem. Commun., 2009,0, 4892-4894
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    A catalytic synthesis of selectively substituted biaryls through sequential intermolecular coupling involving arene and ketone C–H bond functionalization

    G. Maestri, N. Della Ca’ and M. Catellani, Chem. Commun., 2009, 0, 4892
    DOI: 10.1039/B909207B

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