Issue 23, 2009
From the journal:

Chemical Communications

The first total synthesis of (±)-apparicine†‡

M.-Lluïsa Bennasar,*a   Ester Zulaica,a   Daniel Soléa  and  Sandra Alonsoa  

* Corresponding authors

a Laboratory of Organic Chemistry, Faculty of Pharmacy and Institut de Biomedicina (IBUB), University of Barcelona, Spain
E-mail: bennasar@ub.edu.
Fax: +34 93 4024539
Tel: +34 93 4024540

Abstract

The first total synthesis of the indole alkaloidapparicine has been developed through a sequence that includes an indole-templated ring-closing metathesis and a vinylhalideHeck cyclization.

Graphical abstract: The first total synthesis of (±)-apparicine

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Article information

DOI
https://doi.org/10.1039/B903577J
Article type
Communication
Submitted
19 Feb 2009
Accepted
30 Mar 2009
First published
27 Apr 2009

Chem. Commun., 2009, 3372-3374

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The first total synthesis of (±)-apparicine

M.-Lluïsa Bennasar, E. Zulaica, D. Solé and S. Alonso, Chem. Commun., 2009, 3372 DOI: 10.1039/B903577J

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