Issue 8, 2009
From the journal:

Chemical Communications

An efficient copper-catalyzed oxidative Mannich reaction between tertiary amines and methyl ketones†

Youming Shen,a   Mo Li,a   Sizhuo Wang,a   Tianguang Zhan,a   Ze Tan*a  and  Can-Cheng Guo*a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, P. R. China
E-mail: ztanze@gmail.com, ccguo@hnu.cn
Tel: +86 731 8822400

Abstract

An efficient oxidative Mannich reaction between tertiary amines and unmodified methyl ketones has been developed, using copper salts as the catalyst and O2 as the oxidant.

Graphical abstract: An efficient copper-catalyzed oxidative Mannich reaction between tertiary amines and methyl ketones

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Article information

DOI
https://doi.org/10.1039/B819657E
Article type
Communication
Submitted
04 Nov 2008
Accepted
11 Dec 2008
First published
23 Jan 2009

Chem. Commun., 2009, 953-955

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An efficient copper-catalyzed oxidative Mannich reaction between tertiary amines and methyl ketones

Y. Shen, M. Li, S. Wang, T. Zhan, Z. Tan and C. Guo, Chem. Commun., 2009, 953 DOI: 10.1039/B819657E

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