Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 7, 2009
Previous Article Next Article

Synthetic biology: exploring and exploiting genetic modularity through the design of novel biological networks

Author affiliations

Abstract

Synthetic biology has been used to describe many biological endeavors over the past thirty years—from designing enzymes and in vitro systems, to manipulating existing metabolisms and gene expression, to creating entirely synthetic replicating life forms. What separates the current incarnation of synthetic biology from the recombinant DNA technology or metabolic engineering of the past is an emphasis on principles from engineering such as modularity, standardization, and rigorously predictive models. As such, synthetic biology represents a new paradigm for learning about and using biological molecules and data, with applications in basic science, biotechnology, and medicine. This review covers the canonical examples as well as some recent advances in synthetic biology in terms of what we know and what we can learn about the networks underlying biology, and how this endeavor may shape our understanding of living systems.

Graphical abstract: Synthetic biology: exploring and exploiting genetic modularity through the design of novel biological networks

Back to tab navigation

Article information


Submitted
23 Jan 2009
Accepted
27 Apr 2009
First published
14 May 2009

Mol. BioSyst., 2009,5, 704-713
Article type
Review Article

Synthetic biology: exploring and exploiting genetic modularity through the design of novel biological networks

C. M. Agapakis and P. A. Silver, Mol. BioSyst., 2009, 5, 704
DOI: 10.1039/B901484E

Search articles by author

Spotlight

Advertisements