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Issue 13, 2009
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Microfabricating high-aspect-ratio structures in polyurethane-methacrylate (PUMA) disposable microfluidic devices

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Abstract

We recently reported a new UV-curable polyurethane-methacrylate (PUMA) resin that has excellent qualities as a disposable microfluidic substrate for clinical diagnostic applications. This article discusses strategies to improve the production yield of PUMA chips that contain dense and high-aspect-ratio features, which presents unique challenges in demolding and bonding steps. These fabrication improvements were deployed to produce a microfiltration device that contained closely spaced and high-aspect-ratio columns, suitable for retaining and concentrating cells or beads from a highly diluted suspension.

Graphical abstract: Microfabricating high-aspect-ratio structures in polyurethane-methacrylate (PUMA) disposable microfluidic devices

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Article information


Submitted
03 Feb 2009
Accepted
16 Mar 2009
First published
26 Mar 2009

Lab Chip, 2009,9, 1951-1956
Article type
Technical Note

Microfabricating high-aspect-ratio structures in polyurethane-methacrylate (PUMA) disposable microfluidic devices

J. S. Kuo, Y. Zhao, L. Ng, G. S. Yen, R. M. Lorenz, D. S. W. Lim and D. T. Chiu, Lab Chip, 2009, 9, 1951
DOI: 10.1039/B902124H

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