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Issue 1, 2009
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Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system

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Abstract

Most visual screens based on fluorescent markers are currently limited in throughput and accuracy. Here we present the first genetic screen of a mutagenized population of C. elegans in a microfluidic device. Animal handling streamlined by a microfluidic device and intuitive control software enabled the identification of novel mutants and a large screening speed.

Graphical abstract: Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system

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Article information


Submitted
07 Aug 2008
Accepted
17 Oct 2008
First published
27 Oct 2008

Lab Chip, 2009,9, 38-40
Article type
Communication

Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system

M. M. Crane, K. Chung and H. Lu, Lab Chip, 2009, 9, 38
DOI: 10.1039/B813730G

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