A microfluidic 3D hepatocyte chip for drug toxicity testing†
Abstract
We have developed a microfluidic 3D
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* Corresponding authors
a
Institute of Bioengineering and Nanotechnology, A*STAR, The Nanos, #04-01, 31 Biopolis Way, Singapore, Singapore
Fax: +65 6478 9080
Tel: +65 6824 7103
b Department of Physiology, Yong Loo Lin School of Medicine, #03-03, 2 Medical Drive, Singapore, Singapore
c Department of General Surgery, XiangYa Hospital, Central-South University, Changsha, Hunan, China
d Singapore-MIT Alliance, E4-04-10, 4 Engineering Drive 3, Singapore, Singapore
e NUS Tissue-Engineering Programme, DSO Labs, National University of Singapore, Singapore, Singapore
f Department of Haematology-Oncology, National University Hospital, Singapore, Singapore
g Graduate Program in Bioengineering, NUS Graduate School for Integrative Sciences and Engineering, Centre for Life Sciences (CeLS), #05-01, 28 Medical Drive, Singapore, Singapore
h Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
We have developed a microfluidic 3D
Y. Toh, T. C. Lim, D. Tai, G. Xiao, D. van Noort and H. Yu, Lab Chip, 2009, 9, 2026 DOI: 10.1039/B900912D
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