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Issue 4, 2009
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Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

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Abstract

Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.

Graphical abstract: Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

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Publication details

The article was received on 05 Dec 2008, accepted on 22 Jan 2009 and first published on 18 Feb 2009


Article type: Paper
DOI: 10.1039/B821842K
Green Chem., 2009,11, 492-497

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    Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

    L. Carson, P. K. W. Chau, M. J. Earle, M. A. Gilea, B. F. Gilmore, S. P. Gorman, M. T. McCann and K. R. Seddon, Green Chem., 2009, 11, 492
    DOI: 10.1039/B821842K

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