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Issue 6, 2009
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Modern reaction-based indicator systems

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Traditional analyte-specific synthetic receptors or sensors have been developed on the basis of supramolecular interactions (e.g., hydrogen bonding, electrostatics, weak coordinative bonds). Unfortunately, this approach is often subject to limitations. As a result, increasing attention within the chemical sensor community is turning to the use of analyte-specific molecular indicators, wherein substrate-triggered reactions are used to signal the presence of a given analyte. This tutorial review highlights recent reaction-based indicator systems that have been used to detect selected anions, cations, reactive oxygen species, and neutral substrates.

Graphical abstract: Modern reaction-based indicator systems

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Article information

23 Dec 2008
First published
30 Mar 2009

Chem. Soc. Rev., 2009,38, 1647-1662
Article type
Tutorial Review

Modern reaction-based indicator systems

D. Cho and J. L. Sessler, Chem. Soc. Rev., 2009, 38, 1647
DOI: 10.1039/B804436H

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