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Issue 25, 2009

Nucleic acid-induced self-assembly of a platinum(ii) terpyridyl complex: detection of G-quadruplex formation and nuclease activity

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Abstract

A simple “proof-of-principle” concept for the monitoring of G-quadruplex formation and nuclease activity based on the unique self-assembly properties of a platinum(II) terpyridyl complex, has been demonstrated.

Graphical abstract: Nucleic acid-induced self-assembly of a platinum(ii) terpyridyl complex: detection of G-quadruplex formation and nuclease activity

Supplementary files

Article information


Submitted
13 Feb 2009
Accepted
09 Apr 2009
First published
12 May 2009

Chem. Commun., 2009, 3756-3758
Article type
Communication

Nucleic acid-induced self-assembly of a platinum(II) terpyridyl complex: detection of G-quadruplex formation and nuclease activity

C. Yu, K. H. Chan, K. M. Wong and V. W. Yam, Chem. Commun., 2009, 3756 DOI: 10.1039/B903080H

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