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Issue 16, 2009
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Diastereoselective Ritter reactions of chiral secondary benzylicalcohols

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Abstract

An acid-catalysed Ritter reaction of chiral secondary benzylicalcohols enables diastereoselective access to chiral amides, which represent inter alia valuable intermediates for the synthesis of chiral 1,2-diamines and β-amino acids.

Graphical abstract: Diastereoselective Ritter reactions of chiral secondary benzylicalcohols

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Publication details

The article was received on 29 Jan 2009, accepted on 27 Feb 2009 and first published on 17 Mar 2009


Article type: Communication
DOI: 10.1039/B901937E
Chem. Commun., 2009, 2130-2132

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    Diastereoselective Ritter reactions of chiral secondary benzylicalcohols

    P. Rubenbauer and T. Bach, Chem. Commun., 2009, 2130
    DOI: 10.1039/B901937E

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