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Issue 14, 2009
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Asymmetric catalysis with chiral primary amine-based organocatalysts

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Abstract

In the past few years, primary amine catalysts derived from natural amino acids, Cinchona alkaloids and other chiral amines have emerged as readily available, highly versatile and extremely powerful catalysts in asymmetric synthesis. They have been demonstrated to be effective catalysts in a wide range of enantioselective organic reactions. In comparison with secondary amine-mediated transformations, the use of primary amine organocatalysts has often been shown to be complementary or superior.

Graphical abstract: Asymmetric catalysis with chiral primary amine-based organocatalysts

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Article information


Submitted
25 Nov 2008
Accepted
28 Jan 2009
First published
06 Mar 2009

Chem. Commun., 2009, 1807-1821
Article type
Feature Article

Asymmetric catalysis with chiral primary amine-based organocatalysts

L. Xu, J. Luo and Y. Lu, Chem. Commun., 2009, 1807
DOI: 10.1039/B821070E

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