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Issue 14, 2009
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Asymmetric catalysis with chiral primary amine-based organocatalysts

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Abstract

In the past few years, primary amine catalysts derived from natural amino acids, Cinchona alkaloids and other chiral amines have emerged as readily available, highly versatile and extremely powerful catalysts in asymmetric synthesis. They have been demonstrated to be effective catalysts in a wide range of enantioselective organic reactions. In comparison with secondary amine-mediated transformations, the use of primary amine organocatalysts has often been shown to be complementary or superior.

Graphical abstract: Asymmetric catalysis with chiral primary amine-based organocatalysts

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Publication details

The article was received on 25 Nov 2008, accepted on 28 Jan 2009 and first published on 06 Mar 2009


Article type: Feature Article
DOI: 10.1039/B821070E
Chem. Commun., 2009, 1807-1821

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    Asymmetric catalysis with chiral primary amine-based organocatalysts

    L. Xu, J. Luo and Y. Lu, Chem. Commun., 2009, 1807
    DOI: 10.1039/B821070E

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