Issue 6, 2008

Solar one-way photoisomerisation of 5′,8-cyclo-2′-deoxyadenosine

Abstract

Under sunlight irradiation (5′S)-5′,8-cyclo-2′-deoxyadenosine 2 photoisomerises to the (5′R) isomer 1, which is the more easily repaired damage when these cyclopurine lesions are formed in DNA.

Graphical abstract: Solar one-way photoisomerisation of 5′,8-cyclo-2′-deoxyadenosine

Article information

Article type
Paper
Submitted
26 Nov 2007
Accepted
17 Jan 2008
First published
14 Feb 2008

Org. Biomol. Chem., 2008,6, 1083-1086

Solar one-way photoisomerisation of 5′,8-cyclo-2′-deoxyadenosine

L. B. Jimenez, S. Encinas, C. Chatgilialoglu and M. A. Miranda, Org. Biomol. Chem., 2008, 6, 1083 DOI: 10.1039/B718222H

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