Synthesis and testing of chromogenic phenoxazinone substrates for β-alanyl aminopeptidase†
Abstract
Novel 7-N-(β-alanyl)aminophenoxazin-3-one salts 27a–d have been synthesized and tested as chromogenic substrates for β-alanyl
* Corresponding authors
a
Pharmacy, Chemistry and Biomedical Sciences, University of Sunderland, Sunderland, U.K.
E-mail:
paul.groundwater@sunderland.ac.uk
Fax: +44(0)191 515 3405
Tel: +44(0)191 515 2600
b
Department of Microbiology, Freeman Hospital, Newcastle upon Tyne
E-mail:
john.perry@nuth.northy.nhs.uk
Fax: +44(0)191 223 1224
Tel: +44(0)191 284 3111 × 26691
c
R & D Microbiology, bioMerieux, 3 Route del Port Michaud, 28 390 La Balme-les-Grottes, France
E-mail:
sylvain.orenga@eu.biomerieux.com
Fax: +33 (0)474 952 632
Tel: +33 (0)474 952 543
d School of Applied Sciences, Ellison Place, Northumbria University, Newcastle upon Tyne, U.K.
Novel 7-N-(β-alanyl)aminophenoxazin-3-one salts 27a–d have been synthesized and tested as chromogenic substrates for β-alanyl
A. V. Zaytsev, R. J. Anderson, A. Bedernjak, P. W. Groundwater, Y. Huang, J. D. Perry, S. Orenga, C. Roger-Dalbert and A. James, Org. Biomol. Chem., 2008, 6, 682 DOI: 10.1039/B716978G
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