A solid phase synthesis of des-myo-inositol mycothiol disulfide and its alpha-configured methyl- and benzyl-glycoside derivatives has been developed. Kinetic characterisation of these compounds has demonstrated their viability as alternative substrates for use in mycothiol disulfide reductase enzyme assays.
M. J. G. Stewart, V. K. Jothivasan, A. S. Rowan, J. Wagg and C. J. Hamilton, Org. Biomol. Chem., 2008, 6, 385 DOI: 10.1039/B716380K
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