Issue 6, 2008
From the journal:

Molecular BioSystems

2-Methoxycyclopentyl analogues of a Pseudomonas aeruginosaquorum sensing modulator†‡

Lydia Y. W. Lee,a   Timothy Hupfield,a   Rebecca L. Nicholson,a   James T. Hodgkinson,a   Xianbin Su,a   Gemma L. Thomas,a   George P. C. Salmond,b   Martin Welchb  and  David R. Spring*a  

* Corresponding authors

a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK
E-mail: drspring@ch.cam.ac.uk
Tel: +44 (0)1223 336498

b Department of Biochemistry, University of Cambridge, Downing Site, Cambridge, UK

Abstract

Diastereomeric 2-methoxycyclopentyl analogues of a natural quorum sensing signaling molecule from Pseudomonas aeruginosa were synthesized and screened in pigment production assays with P. aeruginosa and Serratia strain ATCC39006.

Graphical abstract: 2-Methoxycyclopentyl analogues of a Pseudomonas aeruginosaquorum sensing modulator

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Article information

DOI
https://doi.org/10.1039/B801563E
Article type
Communication
Submitted
29 Jan 2008
Accepted
29 Feb 2008
First published
18 Mar 2008

Mol. BioSyst., 2008,4, 505-507

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2-Methoxycyclopentyl analogues of a Pseudomonas aeruginosaquorum sensing modulator

L. Y. W. Lee, T. Hupfield, R. L. Nicholson, J. T. Hodgkinson, X. Su, G. L. Thomas, G. P. C. Salmond, M. Welch and D. R. Spring, Mol. BioSyst., 2008, 4, 505 DOI: 10.1039/B801563E

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