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Issue 3, 2008
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Dynamic temperature measurement in microfluidic devices using thermochromic liquid crystals

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Abstract

Thermochromic liquid crystals (TLCs) are used to explore the temperature transients during thermal cycling for microchip-based polymerase chain reaction (PCR). By analyzing the reflected spectra of the TLCs over time, temperature vs. time trajectories were extracted and overshoots/undershoots were estimated. To our knowledge, this is the first report of TLC-based dynamic temperature measurements in a microfluidic device for all PCR temperature stages.

Graphical abstract: Dynamic temperature measurement in microfluidic devices using thermochromic liquid crystals

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Article information


Submitted
07 Sep 2007
Accepted
18 Dec 2007
First published
18 Jan 2008

Lab Chip, 2008,8, 484-487
Article type
Technical Note

Dynamic temperature measurement in microfluidic devices using thermochromic liquid crystals

V. N. Hoang, G. V. Kaigala and C. J. Backhouse, Lab Chip, 2008, 8, 484
DOI: 10.1039/B713764H

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