Issue 3, 2008
From the journal:

Lab on a Chip

Dynamic temperature measurement in microfluidic devices using thermochromic liquid crystals†

Viet N. Hoang,a   Govind V. Kaigalaa  and  Christopher J. Backhouse*a  

* Corresponding authors

a Applied Miniaturisation Laboratory, Department of Electrical and Computer Engineering, University of Edmonton, AB, Canada
E-mail: christopher.backhouse@ualberta.ca
Fax: +1 780 492–1811
Tel: +1 780 492-2920

Abstract

Thermochromic liquid crystals (TLCs) are used to explore the temperature transients during thermal cycling for microchip-based polymerase chain reaction (PCR). By analyzing the reflected spectra of the TLCs over time, temperature vs. time trajectories were extracted and overshoots/undershoots were estimated. To our knowledge, this is the first report of TLC-based dynamic temperature measurements in a microfluidic device for all PCR temperature stages.

Graphical abstract: Dynamic temperature measurement in microfluidic devices using thermochromic liquid crystals

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Article information

DOI
https://doi.org/10.1039/B713764H
Article type
Technical Note
Submitted
07 Sep 2007
Accepted
18 Dec 2007
First published
18 Jan 2008

Lab Chip, 2008,8, 484-487

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Dynamic temperature measurement in microfluidic devices using thermochromic liquid crystals

V. N. Hoang, G. V. Kaigala and C. J. Backhouse, Lab Chip, 2008, 8, 484 DOI: 10.1039/B713764H

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